Tryptophan metabolism in characterized neurones of Helix

Tryptophan metabolism in depression.

Psychiatric patients suffering from endogenous depression and a control group without endogenous depression were given oral loads of L-tryptophan and urinary excretion determined of the tryptophan metabolites on the pyrrolase pathway: kynurenine, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid. Female endogenously depressed subjects excreted significantly more kynurenine and 3-hydroxykynuren...

Tryptophan metabolism in alcoholism.

Studies of tryptophan (Trp) metabolism in relation to the serotonin status in alcoholism are of 2 types: (1) those related to the pharmacological effects of ethanol; (2) those concerning the serotonin status in the absence of alcohol intake. In experimental animals, acute and chronic ethanol administration and subsequent withdrawal exert a variety of effects on brain serotonin synthesis and tur...

Tryptophan Metabolism in Man.

The amino acid tryptophan is unique because it contains the indole nucleus and because it is metabolized in man through several different biochemical pathways to a number of specific products. It is the precursor of serotonin and 5-hydroxyindoleacetic acid. In addition, after cleavage of the indole ring, it may be metabolized by way of the kynurenine pathway to 3-hydroxyanthranilic acid and ult...

The cytology of the neurones of Helix aspersa.

The Cytoplasmlc Inclusions of the Neurones of Helix aspersa

1. The only cytoplasmic inclusions visible in the living neurone are lipid globules and mitochondria. 2. In both Helix and Limnaea there are three kinds of lipid globules, as follows: (a) large globules, yellowish from their carotinoid content; (6) smaller globules, easily coloured by vital dyes; (c) small globules, not colourable by vital dyes. 3. The crescents and rings ('dictyosomes') seen i...